Changes for page Amadee-24-Genes4Mars

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1		-Amadee-24-Genes4Mars
	1	+Amadee-24-RAMSES

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1	1	=== Details ===
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3		-|**Acronym**|Genes4Mars
4		-|**Description**|Astronaut performance and health monitoring with automated ECG andinvestigation of the changes in health-risk-associated gene expression patterns in blood and urine samples of astronauts.
5		-|**Principal Investigator (PI)**|Dr. Arsen Arakelyan ~| [[arsen.arakelyan@rau.am>>mailto:arsen.arakelyan@rau.am]]
6		-|**Organisation** |Institute of Biomedicine and Pharmacy, Russian-Armenian University; Institute of Molecular Biology NAS RA
	3	+|**Acronym**|RAMSES
	4	+|**Description**|Fully autonomous multi-sensor-based helicopter system capable of taking off from a charging dock atop a Mars rover, then conducting aerial reconnaissance for operator-requested POI inspection or autonomous terrain mapping before landing back on the rover to recharge.
	5	+|**Principal Investigator (PI)**|Martin Scheiber ~| [[Martin.Scheiber@aau.at>>mailto:Martin.Scheiber@aau.at]]
	6	+|**Organisation** |Control of Networked Systems Group, Institute of Smart System Technologies, University of Klagenfurt
7	7	|**Co-Investigators**|(((
8		-Karen Avetisyan | [[avetisyan2016@gmail.com>>mailto:avetisyan2016@gmail.com]]
	8	+Marim Faroun | [[mafaroun@edu.aau.at>>mailto:mafaroun@edu.aau.at]]
	9	+
	10	+Tanguy Gerniers | [[t1gerniers@edu.aau.at>>mailto:t1gerniers@edu.aau.at]]
9	9	)))
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11	11	=== Summary ===
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15	15	[[image:ACT_manifest.png||height="266" width="399"]]
16	16	)))
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18		-Long-term space missions are known to be associated with health risks to astronauts because of environmental factors, such as radiation, microgravity, and lasting isolation. These risks could be more aggravating during spaceexplorationmissions, e.g.to Mars, especially with limited access to healthcare facilities. It is suspected that space flights and planetary missions could have performance degradation and negative effects on the cardiovascular health of the crew.Therefore, the development of biomarker-based and physiological predictors of health risks for the assessment of physiological conditions is of vital importance.
	20	+In 2021, the first Uncrewed Aerial Vehicle (UAV) performed its first flight on Mars. With this flight, Ingenuity developed by NASA, proved that VTOL aircraft can operate under Martian conditions. However, furtherresearch and development is necessary to take out full advantage of flying vehicles during a Mars mission.
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20		-The main objective of Genes4Mars is a retrospective investigation of changes inrisk-associated gene expression patterns in blood and urine samples from the Analog Astronauts. It will also investigate how well automated electrocardiogram (ECG)analysis can be used to monitor astronaut performanceduring planetary missions, and whether ECG can be used as a surrogate marker for dynamic changes in cardiacfunction-related genes. The members of the flight crew could be considered as a case group and the back-up flight crew members could function as a control group. The samples will be collected from each participant at multiple time points pre-, during and past-mission and will be analysed after the mission is completed. RNA will be extracted from the samples immediately upon their transfer to the lab and analysed for up-or downregulated genes. Additionally, 12-lead and single-lead ECGs of each participant should be taken one week prior to the start of the mission and each day before and after field assignments outside the habitat. After the end of the mission, the data will be analysed using deep learning methods and pre-trained models to detect heart pathologies. Correlation and regression analysis will be used to find the association between gene expression and physiological parameters.
	22	+The Rover Aerial Mars Support and Exploration System (RAM-SES) is a technology system for future UAVs using an AI-based network to autonomously detect landing sites in Mars-like environments. With participation in AMADEE-24, RAMSES’s novel approach demonstrates the process of detecting visual points of interest, either scientifically or for safe UAV navigation.
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	24	+The expected outcome is to utilize an AI-based network togenerate a heat map for successfully detecting landing sites inthe mission area. Additionally, the system contains gener-ated pixel-wise maps and provides comprehensive and detaileddepictions of scientific points of interest in Mars-like environments. RAMSES evaluates data gathered by other robotic vehicles to create the aforementioned heat map and points of interest. In turn, this data can enhance the mission capabilities ofother teams to further demonstrate collaboration between experiments.
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	26	+To achieve the defined experiment objectives within AMADEE-24,RAMSES focuses on evaluating data gathered by the SAMPLE experiment. With the help of the ground truth of the mission area data,we are able to compare the system’s pixel-wise map coordinates andimprove the precision of the location of notable features for scientific research in order to contribute to the advancement of scientificknowledge about the environment. In the context of collaborative experimentation, RAMSES shall be subjected to proof-of-concept teststhat aim to exhibit its capabilities in supporting AMADEE-24 andfuture missions.
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26	26	=== Experiment Data ===