Changes for page Amadee-24-Genes4Mars

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1		-Amadee-24-EIEE –Emotions in Extreme Environment
	1	+Amadee-24-Genes4Mars

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1	1	=== Details ===
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3		-|**Acronym**|EIEE –Emotions in Extreme Environment
4		-|**Description**|AAintrinsic/extrinsic emotion regulationstrategies, using CERQ questionnaire +audio recordings, emotion listing andlogbook in the evening.
5		-|**Principal Investigator (PI)**|Alexandra De Carvalho ~| [[alexsitadecarvalho@gmail.com>>mailto:alexsitadecarvalho@gmail.com]]
6		-|**Organisation** |Austrian Space Forum
	3	+|**Acronym**|Genes4Mars
	4	+|**Description**|Astronaut performance and health monitoring with automated ECG andinvestigation of the changes in health-risk-associated gene expression patterns in blood and urine samples of astronauts.
	5	+|**Principal Investigator (PI)**|Dr. Arsen Arakelyan ~| [[arsen.arakelyan@rau.am>>mailto:arsen.arakelyan@rau.am]]
	6	+|**Organisation** |Institute of Biomedicine and Pharmacy, Russian-Armenian University; Institute of Molecular Biology NAS RA
7	7	|**Co-Investigators**|(((
8		-Sylwia Kaduk/ ÖWF Human Factors Team | [[sylwiaizabela.kaduk@ext.esa.int>>mailto:sylwiaizabela.kaduk@ext.esa.int]]
9		-
10		-Aisha Animashaun/ ÖWF Human Factors Team | [[aisha.animashaun@outlook.de>>mailto:aisha.animashaun@outlook.de]]
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12		-Phil Brady/ ÖWF Human Factors Team | [[drphilipbrady@gmail.com>>mailto:drphilipbrady@gmail.com]]
13		-
14		-Annabelle Mielitz/ ÖWF Human Factors Team | [[annabelle@mielitz.de>>mailto:annabelle@mielitz.de]]
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16		-Nael Radwan/ ÖWF Human Factors Team | [[nael.radwan@hotmail.com>>mailto:nael.radwan@hotmail.com]]
	8	+Karen Avetisyan | [[avetisyan2016@gmail.com>>mailto:avetisyan2016@gmail.com]]
17	17	)))
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19	19	=== Summary ===
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23	23	[[image:ACT_manifest.png||height="266" width="399"]]
24	24	)))
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26		-The focus of space psychological studies mostly lies on stress processing or performance-related measures. Emotions were not investigated properly. Even in astronautical spaceflight they have not played a major role yet. However, dealing with emotions, especially on long-term missions and extreme environments, is crucial to one’s performance, well-being, and interpersonal relationships.
	18	+Long-term space missions are known to be associated with health risks to astronauts because of environmental factors, such as radiation, microgravity, and lasting isolation. These risks could be more aggravating during spaceexplorationmissions, e.g.to Mars, especially with limited access to healthcare facilities. It is suspected that space flights and planetary missions could have performance degradation and negative effects on the cardiovascular health of the crew.Therefore, the development of biomarker-based and physiological predictors of health risks for the assessment of physiological conditions is of vital importance.
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28		-EIEE aims to investigate what emotions analog astronauts experience and what strategies they use to deal with them. It will also investigate if and how those strategies change over time in stressful situations. The analysis of emotion regulation strategies can help to work out programs and trainings for future Mars missions to mitigate emerging problems.
	20	+The main objective of Genes4Mars is a retrospective investigation of changes inrisk-associated gene expression patterns in blood and urine samples from the Analog Astronauts. It will also investigate how well automated electrocardiogram (ECG)analysis can be used to monitor astronaut performanceduring planetary missions, and whether ECG can be used as a surrogate marker for dynamic changes in cardiacfunction-related genes. The members of the flight crew could be considered as a case group and the back-up flight crew members could function as a control group. The samples will be collected from each participant at multiple time points pre-, during and past-mission and will be analysed after the mission is completed. RNA will be extracted from the samples immediately upon their transfer to the lab and analysed for up-or downregulated genes. Additionally, 12-lead and single-lead ECGs of each participant should be taken one week prior to the start of the mission and each day before and after field assignments outside the habitat. After the end of the mission, the data will be analysed using deep learning methods and pre-trained models to detect heart pathologies. Correlation and regression analysis will be used to find the association between gene expression and physiological parameters.
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30		-The study will provide detailed insight into the emotional experience and regulation strategies applied by analog astronauts during a mission in an extreme environment.
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32		-Before the mission, analog astronauts will complete the “Cognitive Emotion Regulation Questionnaire” (CERQ) and open questions related to the upcoming mission. During the mission, the analog astronauts have to keep a structured daily diary or audio log that asks about emotions and emotion regulation strategies. They will also use an emotion list daily to name which emotions they have experienced and to what intensity. After the mission, the CERQ will be completed again by the analog astronauts.
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34	34	=== Experiment Data ===
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